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Abstract

In March 2024, the French genomic surveillance of enteric yersiniosis identified a cluster of lineage 2/3–9b isolates, corresponding to bioserotype 2/O:9. An outbreak investigation was conducted to identify the source and implement control measures. A total of 175 confirmed cases were identified in France with sampling dates between 27 January and 23 August. Case interviews and trace-back investigations identified unpasteurised soft goat’s milk cheese from one manufacturer in France as the probable source of the outbreak. belonging to the same cluster as the case isolates was isolated from 23 samples from the manufacturer and a goat farm supplying milk to the dairy. Cheeses from the manufacturer were recalled in France. A Rapid Alert System for Food and Feed (RASFF) notification was issued, allowing the identification of cheese distribution from the manufacturer to 29 countries. An Epipulse alert led to the identification of seven additional cases in Belgium, Luxembourg and Norway, illustrating the value of international warning systems. This outbreak demonstrates risks with consumption of unpasteurised cheese and emphasises the need of rigorous good hygiene practices on dairy farms and dairies, especially when milk is processed without pasteurisation.

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/content/10.2807/1560-7917.ES.2025.30.26.2500002
2025-07-03
2025-07-25
/content/10.2807/1560-7917.ES.2025.30.26.2500002
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References

  1. Moura A, Criscuolo A, Pouseele H, Maury MM, Leclercq A, Tarr C, et al. Whole genome-based population biology and epidemiological surveillance of Listeria monocytogenes. Nat Microbiol. 2016;2(2):16185.  https://doi.org/10.1038/nmicrobiol.2016.185  PMID: 27723724 
  2. Le Guern AS, Savin C, Chereau F, Tessier S, Guglielmini J, Brémont S, et al. A novel cgMLST for genomic surveillance of Yersinia enterocolitica infections in France allowed the detection and investigation of outbreaks in 2017-2021. Microbiol Spectr. 2024;12(6):e0050424.  https://doi.org/10.1128/spectrum.00504-24  PMID: 38651883 
  3. Yassine I, Lefèvre S, Hansen EE, Ruckly C, Carle I, Lejay-Collin M, et al. Population structure analysis and laboratory monitoring of Shigella by core-genome multilocus sequence typing. Nat Commun. 2022;13(1):551.  https://doi.org/10.1038/s41467-022-28121-1  PMID: 35087053 
  4. Cover TL, Aber RC. Yersinia enterocolitica. N Engl J Med. 1989;321(1):16-24.  https://doi.org/10.1056/NEJM198907063210104  PMID: 2659991 
  5. Rosner BM, Werber D, Höhle M, Stark K. Clinical aspects and self-reported symptoms of sequelae of Yersinia enterocolitica infections in a population-based study, Germany 2009-2010. BMC Infect Dis. 2013;13(1):236.  https://doi.org/10.1186/1471-2334-13-236  PMID: 23701958 
  6. European Food Safety Authority (EFSA)European Centre for Disease Prevention and Control (ECDC). The European Union One Health 2022 Zoonoses Report. EFSA J. 2023;21(12):e8442. PMID: 38089471 
  7. Grahek-Ogden D, Schimmer B, Cudjoe KS, Nygård K, Kapperud G. Outbreak of Yersinia enterocolitica serogroup O:9 infection and processed pork, Norway. Emerg Infect Dis. 2007;13(5):754-6.  https://doi.org/10.3201/eid1305.061062  PMID: 17553258 
  8. Longenberger AH, Gronostaj MP, Yee GY, Johnson LM, Lando JF, Voorhees RE, et al. Yersinia enterocolitica infections associated with improperly pasteurized milk products: southwest Pennsylvania, March-August, 2011. Epidemiol Infect. 2014;142(8):1640-50.  https://doi.org/10.1017/S0950268813002616  PMID: 24128938 
  9. MacDonald E, Einöder-Moreno M, Borgen K, Thorstensen Brandal L, Diab L, Fossli Ø, et al. National outbreak of Yersinia enterocolitica infections in military and civilian populations associated with consumption of mixed salad, Norway, 2014. Euro Surveill. 2016;21(34):30321.  https://doi.org/10.2807/1560-7917.ES.2016.21.34.30321  PMID: 27588690 
  10. Williamson DA, Baines SL, Carter GP, da Silva AG, Ren X, Sherwood J, et al. Genomic insights into a sustained national outbreak of Yersinia pseudotuberculosis. Genome Biol Evol. 2016;8(12):3806-14. PMID: 28173076 
  11. Savin C, Criscuolo A, Guglielmini J, Le Guern AS, Carniel E, Pizarro-Cerdá J, et al. Genus-wide Yersinia core-genome multilocus sequence typing for species identification and strain characterization. Microb Genom. 2019;5(10):e000301.  https://doi.org/10.1099/mgen.0.000301  PMID: 31580794 
  12. Hallanvuo S, Herranen M, Jaakkonen A, Nummela M, Ranta J, Interlaboratory study group, et al. Validation of EN ISO method 10273 - Detection of pathogenic Yersinia enterocolitica in foods. Int J Food Microbiol. 2019;288:66-74.  https://doi.org/10.1016/j.ijfoodmicro.2018.01.009  PMID: 29395387 
  13. Weagant SD. A new chromogenic agar medium for detection of potentially virulent Yersinia enterocolitica. J Microbiol Methods. 2008;72(2):185-90.  https://doi.org/10.1016/j.mimet.2007.11.019  PMID: 18177960 
  14. Wauters G, Kandolo K, Janssens M. Revised biogrouping scheme of Yersinia enterocolitica. Contrib Microbiol Immunol. 1987;9:14-21. PMID: 3665492 
  15. Jolley KA, Bray JE, Maiden MCJ. Open-access bacterial population genomics: BIGSdb software, the PubMLST.org website and their applications. Wellcome Open Res. 2018;3:124.  https://doi.org/10.12688/wellcomeopenres.14826.1  PMID: 30345391 
  16. Guinet F, Carniel E, Leclercq A. Transfusion-transmitted Yersinia enterocolitica sepsis. Clin Infect Dis. 2011;53(6):583-91.  https://doi.org/10.1093/cid/cir452  PMID: 21865196 
  17. Ackers ML, Schoenfeld S, Markman J, Smith MG, Nicholson MA, DeWitt W, et al. An outbreak of Yersinia enterocolitica O:8 infections associated with pasteurized milk. J Infect Dis. 2000;181(5):1834-7.  https://doi.org/10.1086/315436  PMID: 10823796 
  18. Gruber JF, Morris S, Warren KA, Kline KE, Schroeder B, Dettinger L, et al. Yersinia enterocolitica outbreak associated with pasteurized milk. Foodborne Pathog Dis. 2021;18(7):448-54.  https://doi.org/10.1089/fpd.2020.2924  PMID: 33904765 
  19. Bonardi S, Le Guern AS, Savin C, Pupillo G, Bolzoni L, Cavalca M, et al. Detection, virulence and antimicrobial resistance of Yersinia enterocolitica in bulk tank milk in Italy. Int Dairy J. 2018;84:46-53.  https://doi.org/10.1016/j.idairyj.2018.04.003 
  20. Le Guern AS, Martin L, Savin C, Carniel E. Yersiniosis in France: overview and potential sources of infection. Int J Infect Dis. 2016;46:1-7. "%20https://dx.doi.org/10.1016/j.ijid.2016.03.008%20PMID:26987478" https://doi.org/10.1016/j.ijid.2016.03.008  PMID: 26987478 
  21. Chart H, Cheasty T. The serodiagnosis of human infections with Yersinia enterocolitica and Yersinia pseudotuberculosis. FEMS Immunol Med Microbiol. 2006;47(3):391-7.  https://doi.org/10.1111/j.1574-695X.2006.00100.x  PMID: 16872375 
Cross-border outbreak of Yersinia enterocolitica bioserotype 2/O:9 infections associated with consumption of French unpasteurised soft goat’s milk cheese, 2024
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Cyril+Savin&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Savin Cyril</a>, <a href="/search?value1=Nathalie+Fredriksen&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Fredriksen Nathalie</a>, <a href="/search?value1=Cl%C3%A9mentine+Calba&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Calba Clémentine</a>, <a href="/search?value1=Lorraine+Puzin&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Puzin Lorraine</a>, <a href="/search?value1=Arnaud+Felten&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Felten Arnaud</a>, <a href="/search?value1=St%C3%A9phane+Larr%C3%A9ch%C3%A9&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Larréché Stéphane</a>, <a href="/search?value1=Anthony+Roche&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Roche Anthony</a>, <a href="/search?value1=Martine+Denis&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Denis Martine</a>, <a href="/search?value1=Anne-Sophie+Le+Guern&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Le Guern Anne-Sophie</a>, <a href="/search?value1=Fanny+Chereau&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Chereau Fanny</a>, <a href="/search?value1=Y.+enterocolitica+Outbreak+Investigation+Group&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Y. enterocolitica Outbreak Investigation Group</a></span>. Cross-border outbreak of Yersinia enterocolitica bioserotype 2/O:9 infections associated with consumption of French unpasteurised soft goat’s milk cheese, 2024. <a href="/content/ecdc">Euro Surveill.</a> 2025;30(26):pii=2500002. <a href="https://doi.org/10.2807/1560-7917.ES.2025.30.26.2500002" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2025.30.26.2500002</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 20 Dec 2024;&nbsp;&nbsp; <span class="generated">Accepted</span>: 04 Mar 2025 </span> </p>
/content/10.2807/1560-7917.ES.2025.30.26.2500002
/content/10.2807/1560-7917.ES.2025.30.26.2500002
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