Application in Europe of a urine-based rapid diagnostic test for confirmation of Schistosoma mansoni infection in migrants from endemic areas

S L Becker; H Marti; S Zimmermann; D Vidacek; M Herrmann; J Utzinger; P A Schnabel; R M Bohle

doi:10.2807/1560-7917.ES2015.20.23.21151

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Application in Europe of a urine-based rapid diagnostic test for confirmation of Schistosoma mansoni infection in migrants from endemic areas
S L Becker^1,2,3 , H Marti^3,4 , S Zimmermann⁵ , D Vidacek⁵ , M Herrmann¹ , J Utzinger^2,3 , P A Schnabel⁶ , R M Bohle⁶
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Affiliations: ¹ Institute of Medical Microbiology and Hygiene, Saarland University, Homburg/Saar, Germany ² Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland ³ University of Basel, Basel, Switzerland ⁴ Department of Medical Services and Diagnostic, Swiss Tropical and Public Health Institute, Basel, Switzerland ⁵ Department of Medicine II, Saarland University, Homburg/Saar, Germany ⁶ Institute of Pathology, Saarland University, Homburg/Saar, Germany

Correspondence:
S Becker
soeren.becker uks.eu
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Citation style for this article: Becker S L, Marti H, Zimmermann S, Vidacek D, Herrmann M, Utzinger J, Schnabel P A, Bohle R M. Application in Europe of a urine-based rapid diagnostic test for confirmation of Schistosoma mansoni infection in migrants from endemic areas. Euro Surveill. 2015;20(23):pii=21151. https://doi.org/10.2807/1560-7917.ES2015.20.23.21151 Received: 27 May 2015

Abstract

In February 2015, a male patient from Eritrea with persistent abdominal pain and rectal bleeding was diagnosed with Schistosoma mansoni infection upon examination of a rectal biopsy. In May 2015, repeated stool microscopy identified S. mansoni infection in another Eritrean patient with abdominal pain and considerable eosinophilia (34%). Use of point-of-care circulating cathodic antigen (POC-CCA) tests on urine confirmed S. mansoni infection in both patients. Wider application of non-invasive POC-CCA urine tests will improve schistosomiasis diagnosis and clinical management in migrants.