Emergence of a new GII.17 norovirus variant in patients with acute gastroenteritis in Jiangsu, China, September 2014 to March 2015

J Fu; J Ai; M Jin; C Jiang; J Zhang; C Shi; Q Lin; Z Yuan; X Qi; C Bao; F Tang; Y Zhu

doi:10.2807/1560-7917.ES2015.20.24.21157

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Emergence of a new GII.17 norovirus variant in patients with acute gastroenteritis in Jiangsu, China, September 2014 to March 2015

J Fu^1,2, J Ai^1,2, M Jin³, C Jiang⁴, J Zhang⁵, C Shi⁶, Q Lin⁷, Z Yuan⁸, X Qi¹, C Bao¹, F Tang¹, Y Zhu¹
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Affiliations: ¹ Key Lab of Enteric Pathogenic Microbiology, Ministry of Health, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing, China ² These authors contributed equally to this work ³ Institute for Viral Diseases Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China ⁴ Nanjing Maternity and Child Health Care Hospital, Nanjing, China ⁵ Suzhou Center for Disease Control and Prevention, Suzhou, China ⁶ Wuxi Center for Disease Control and Prevention, Wuxi, China ⁷ Changzhou Center for Disease Control and Prevention, Changzhou, China ⁸ Zhenjiang Center for Disease Control and Prevention, Zhenjiang, China

Correspondence:
Y Zhu
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Citation style for this article: Fu J, Ai J, Jin M, Jiang C, Zhang J, Shi C, Lin Q, Yuan Z, Qi X, Bao C, Tang F, Zhu Y. Emergence of a new GII.17 norovirus variant in patients with acute gastroenteritis in Jiangsu, China, September 2014 to March 2015. Euro Surveill. 2015;20(24):pii=21157. https://doi.org/10.2807/1560-7917.ES2015.20.24.21157 Received: 27 May 2015

Abstract

From September 2014 to March 2015, 23 outbreaks of norovirus (NoV) acute gastroenteritis occurred in Jiangsu, China. Partial sequencing of the NoV capsid gene suggested that 16 of the 23 outbreaks were related to a new GII.17 variant. This variant was first detected in sporadic specimens in October 2014, and became predominant in February 2015. Analysis of the RNA-dependent RNA polymerase (RdRp), and complete capsid including the protruding domain P2 sequences confirmed this GII.17 variant as distinct from previously identified GII variants.