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Abstract

A teenage woman migrating from Syria arrived in May 2015 in Germany. She gave birth to a healthy child in early 2016, but became febrile shortly after delivery. Blood cultures revealed In retrospect, she reported contact with sheep in Syria and recurrent pain in the hip joints over about five months before diagnosis of brucellosis. We discuss consequences for adequate treatment of mother and child as well as for clinical and laboratory management.

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/content/10.2807/1560-7917.ES.2016.21.31.30311
2016-08-04
2024-03-19
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2016.21.31.30311
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References

  1. Pappas G, Papadimitriou P, Akritidis N, Christou L, Tsianos EV. The new global map of human brucellosis. Lancet Infect Dis. 2006;6(2):91-9.  https://doi.org/10.1016/S1473-3099(06)70382-6  PMID: 16439329 
  2. Garofolo G, Fasanella A, Di Giannatale E, Platone I, Sacchini L, Persiani T, et al. Cases of human brucellosis in Sweden linked to Middle East and Africa. BMC Res Notes. 2016;9(1):277.  https://doi.org/10.1186/s13104-016-2074-7  PMID: 27188619 
  3. Norman FF, Monge-Maillo B, Chamorro-Tojeiro S, Pérez-Molina JA, López-Vélez R. Imported brucellosis: A case series and literature review. Travel Med Infect Dis. 2016;14(3):182-99.  https://doi.org/10.1016/j.tmaid.2016.05.005  PMID: 27185403 
  4. Garcell HG, Garcia EG, Pueyo PV, Martín IR, Arias AV, Alfonso Serrano RN. Outbreaks of brucellosis related to the consumption of unpasteurized camel milk. J Infect Public Health. 2016;9(4):523-7.  https://doi.org/10.1016/j.jiph.2015.12.006  PMID: 26796768 
  5. Al Dahouk S, Neubauer H, Hensel A, Schöneberg I, Nöckler K, Alpers K, et al. Changing epidemiology of human brucellosis, Germany, 1962-2005. Emerg Infect Dis. 2007;13(12):1895-900.  https://doi.org/10.3201/eid1312.070527  PMID: 18258041 
  6. Bosilkovski M, Krteva L, Caparoska S, Labacevski N, Petrovski M. Childhood brucellosis: Review of 317 cases. Asian Pac J Trop Med. 2015;8(12):1027-32.  https://doi.org/10.1016/j.apjtm.2015.11.009  PMID: 26706674 
  7. Cacace ML, Claros EA, Erazu KA, Escobar GI, Lucero NE. Congenital brucellosis in an infant. Vector Borne Zoonotic Dis. 2013;13(7):513-5.  https://doi.org/10.1089/vbz.2012.1165  PMID: 23590322 
  8. Kim JY, Kang SI, Lee JJ, Lee K, Sung SR, Erdenebaataar J, et al. Differential diagnosis of Brucella abortus by real-time PCR based on a single-nucleotide polymorphisms. J Vet Med Sci. 2016;78(4):557-62.  https://doi.org/10.1292/jvms.15-0541  PMID: 26666176 
  9. Piranfar V, Sharif M, Hashemi M, Vahdati AR, Mirnejad R. Detection and discrimination of two Brucella species by multiplex real-time PCR and high-resolution melt analysis curve from human blood and comparison of results using RFLP. Iran J Basic Med Sci. 2015;18(9):909-14. PMID: 26523223 
  10. Hänsel C, Mertens K, Elschner MC, Melzer F. Novel real-time PCR detection assay for Brucella suis. Vet Rec Open. 2015;2(1):e000084.  https://doi.org/10.1136/vetreco-2014-000084  PMID: 26392898 
  11. Lasch P, Wahab T, Weil S, Pályi B, Tomaso H, Zange S, et al. Identification of highly pathogenic microorganisms by matrix-assisted laser desorption Ionization-time of flight mass spectrometry: Results of an interlaboratory ring trial. J Clin Microbiol. 2015;53(8):2632-40.  https://doi.org/10.1128/JCM.00813-15  PMID: 26063856 
  12. Karger A, Melzer F, Timke M, Bettin B, Kostrzewa M, Nöckler K, et al. Interlaboratory comparison of intact-cell matrix-assisted laser desorption ionization-time of flight mass spectrometry results for identification and differentiation of Brucella spp. J Clin Microbiol. 2013;51(9):3123-6.  https://doi.org/10.1128/JCM.01720-13  PMID: 23850950 
  13. Mesureur J, Ranaldi S, Monnin V, Girard V, Arend S, Welker M, et al. A Simple and safe protocol for preparing Brucella samples for matrix-assisted laser desorption Ionization-time of flight mass spectrometry analysis. J Clin Microbiol. 2016;54(2):449-52.  https://doi.org/10.1128/JCM.02730-15  PMID: 26582837 
  14. Scholz HC, Vergnaud G. Molecular characterisation of Brucella species. Rev Sci Tech. 2013;32(1):149-62.  https://doi.org/10.20506/rst.32.1.2189  PMID: 23837373 
  15. Garofolo G, Di Giannatale E, De Massis F, Zilli K, Ancora M, Cammà C, et al. Investigating genetic diversity of Brucella abortus and Brucella melitensis in Italy with MLVA-16. Infect Genet Evol. 2013;19:59-70.  https://doi.org/10.1016/j.meegid.2013.06.021  PMID: 23831636 
  16. Al Dahouk S, Sprague LD, Neubauer H. New developments in the diagnostic procedures for zoonotic brucellosis in humans. Rev Sci Tech. 2013;32(1):177-88.  https://doi.org/10.20506/rst.32.1.2204  PMID: 23837375 
  17. Solís García Del Pozo J, Lorente Ortuño S, Navarro E, Solera J. Detection of IgM antibrucella antibody in the absence of IgGs: a challenge for the clinical interpretation of brucella serology. PLoS Negl Trop Dis. 2014;8(12):e3390.  https://doi.org/10.1371/journal.pntd.0003390  PMID: 25474572 
  18. Lowe CF, Showler AJ, Perera S, McIntyre S, Qureshi R, Patel SN, et al. Hospital-associated transmission of Brucella melitensis outside the laboratory. Emerg Infect Dis. 2015;21(1):150-2.  https://doi.org/10.3201/eid2101.141247  PMID: 25531198 
  19. Yagupsky P, Baron EJ. Laboratory exposures to brucellae and implications for bioterrorism. Emerg Infect Dis. 2005;11(8):1180-5.  https://doi.org/10.3201/eid1108.041197  PMID: 16102304 
  20. Traxler RM, Lehman MW, Bosserman EA, Guerra MA, Smith TL. A literature review of laboratory-acquired brucellosis. J Clin Microbiol. 2013;51(9):3055-62.  https://doi.org/10.1128/JCM.00135-13  PMID: 23824774 
  21. Singh K. Laboratory-acquired infections. Clin Infect Dis. 2009;49(1):142-7.  https://doi.org/10.1086/599104  PMID: 19480580 
  22. Regulations DG. (DGR). International Air Transport Association (IATA); 2016. Available from: http://www.iata.org/publications/dgr/Pages/manuals.aspx
  23. European Agreement concerning the International Carriage of Dangerous Goods by Road. ADR applicable as from 1 January 2015. Geneva: United Nations Economic Commission for Europe (UNECE); 2015. Available from: http://www.unece.org/trans/danger/publi/adr/adr2015/15contentse.html
  24. Rhodes HM, Williams DN, Hansen GT. Invasive human brucellosis infection in travelers to and immigrants from the Horn of Africa related to the consumption of raw camel milk. Travel Med Infect Dis. 2016;14(3):255-60.  https://doi.org/10.1016/j.tmaid.2016.03.013  PMID: 27038818 
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