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Abstract

The United Kingdom is introducing a universal annual influenza vaccination programme for children. Live attenuated influenza vaccine (LAIV) effectiveness (VE) against laboratory-confirmed influenza hospitalisation in 2 to 6 year-olds in England was measured in 2015/16 using the screening method. VE adjusted for age, geography and month was 54.5% (95% confidence interval (CI): 31.5% to 68.4%) for all influenza types combined; 48.3% (95% CI: 16.9% to 67.8%) for A(H1N1)pdm09 and 70.6% (95% CI: 33.2% to 87.1%) for B. The findings support on-going programme roll-out.

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/content/10.2807/1560-7917.ES.2017.22.4.30450
2017-01-26
2020-04-04
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2017.22.4.30450
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Live attenuated influenza vaccine effectiveness against hospitalisation due to laboratory-confirmed influenza in children two to six years of age in England in the 2015/16 season
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Richard+Pebody&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Pebody Richard</a>, <a href="/search?value1=Bersabeh+Sile&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Sile Bersabeh</a>, <a href="/search?value1=Fiona+Warburton&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Warburton Fiona</a>, <a href="/search?value1=Mary+Sinnathamby&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Sinnathamby Mary</a>, <a href="/search?value1=Camille+Tsang&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Tsang Camille</a>, <a href="/search?value1=Hongxin+Zhao&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Zhao Hongxin</a>, <a href="/search?value1=Joanna+Ellis&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Ellis Joanna</a>, <a href="/search?value1=Nick+Andrews&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Andrews Nick</a></span>. Live attenuated influenza vaccine effectiveness against hospitalisation due to laboratory-confirmed influenza in children two to six years of age in England in the 2015/16 season. <a href="/content/ecdc">Euro Surveill.</a> 2017;22(4):pii=30450. <a href="https://doi.org/10.2807/1560-7917.ES.2017.22.4.30450" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2017.22.4.30450</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 09 Dec 2016;&nbsp;&nbsp; <span class="generated">Accepted</span>: 18 Jan 2017 </span> </p>
/content/10.2807/1560-7917.ES.2017.22.4.30450
/content/10.2807/1560-7917.ES.2017.22.4.30450
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