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Abstract

A large outbreak of vancomycin-resistant enterococci (VRE) is affecting four hospitals in the Canton of Bern, Switzerland, since December 2017. Of 89 cases identified as carriers, 77 (86.5%) VRE isolates were virtually indistinguishable using whole genome sequencing, and identified as multilocus sequence type (MLST) ST796. This clone, previously only described in Australia and New Zealand, is characterised by rapid spread and the ability to cause bloodstream infections. It requires a multifaceted infection prevention effort.

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/content/10.2807/1560-7917.ES.2018.23.29.1800351
2018-07-19
2020-07-03
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2018.23.29.1800351
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Outbreak of vancomycin-resistant Enterococcus faecium clone ST796, Switzerland, December 2017 to April 2018
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Nasstasja+Wassilew&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Wassilew Nasstasja</a> , <a href="/search?value1=Helena+MB+Seth-Smith&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Seth-Smith Helena MB</a> , <a href="/search?value1=Eveline+Rolli&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Rolli Eveline</a> , <a href="/search?value1=Yvonne+Fietze&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Fietze Yvonne</a> , <a href="/search?value1=Carlo+Casanova&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Casanova Carlo</a> , <a href="/search?value1=Urs+F%C3%BChrer&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Führer Urs</a> , <a href="/search?value1=Adrian+Egli&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Egli Adrian</a> , <a href="/search?value1=Jonas+Marschall&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Marschall Jonas</a> , <a href="/search?value1=Niccol%C3%B2+Buetti&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Buetti Niccolò</a> </span>. Outbreak of vancomycin-resistant Enterococcus faecium clone ST796, Switzerland, December 2017 to April 2018. <a href="/content/ecdc">Euro Surveill.</a> 2018;23(29):pii=1800351. <a href="https://doi.org/10.2807/1560-7917.ES.2018.23.29.1800351" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2018.23.29.1800351</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 02 Jul 2018;&nbsp;&nbsp; <span class="generated">Accepted</span>: 19 Jul 2018 </span> </p>
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/content/10.2807/1560-7917.ES.2018.23.29.1800351
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Supplementary data

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    • Table S1. List of isolates and associated genomic parameters

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    • Figure S1. Phylogeny of ST796 based on SNPs, relative to the reference sequence Ef_aus0233

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