1887
  1. Home
  2. Eurosurveillance
  3. Volume 24, Issue 9, 28/Feb/2019
  4. Article
Rapid communication Open Access
Like 1
Download

Abstract

A survey on the epidemiological situation, surveillance and containment activities for carbapenemase-producing Enterobacteriaceae (CPE) was conducted in European countries in 2018. All 37 participating countries reported CPE cases. Since 2015, the epidemiological stage of CPE expansion has increased in 11 countries. Reference laboratory capability, dedicated surveillance and a specific national containment plan are in existence in 33, 27 and 14 countries, respectively. Enhanced control efforts are needed for CPE containment in Europe.

© Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Loading

Article metrics loading...

/content/10.2807/1560-7917.ES.2019.24.9.1900123
2019-02-28
2019-08-23
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2019.24.9.1900123
Loading
Loading full text...

Full text loading...

/deliver/fulltext/eurosurveillance/24/9/eurosurv-24-9-3.html?itemId=/content/10.2807/1560-7917.ES.2019.24.9.1900123&mimeType=html&fmt=ahah

References

  1. European Centre for Disease Prevention and Control (ECDC). Carbapenem-resistant Enterobacteriacae, first update. Rapid risk assessment. Stockholm: ECDC; 2018. Available from: https://ecdc.europa.eu/sites/portal/files/documents/RRA-Enterobacteriaceae-Carbapenems-European-Union-countries.pdf
  2. Logan LK, Weinstein RA. The epidemiology of carbapenem-resistant Enterobacteriaceae: The impact and evolution of a global menace. J Infect Dis. 2017;215(suppl_1):S28-36.  https://doi.org/10.1093/infdis/jiw282  PMID: 28375512 
  3. European Centre for Disease Prevention and Control (ECDC). Surveillance of antimicrobial resistance in Europe. Annual report of the European Antimicrobial Resistance Surveillance Network (EARS-Net) 2017. Stockholm: ECDC; 2018. Available from: https://ecdc.europa.eu/sites/portal/files/documents/AMR-surveillance-EARS-Net-2017.pdf
  4. Guducuoglu H, Gursoy NC, Yakupogullari Y, Parlak M, Karasin G, Sunnetcioglu M, et al. Hospital outbreak of a colistin-resistant, NDM-1- and OXA-48-producing Klebsiella pneumoniae: high mortality from pandrug resistance. Microb Drug Resist. 2018;24(7):966-72.  https://doi.org/10.1089/mdr.2017.0173  PMID: 29265963 
  5. Avgoulea K, Di Pilato V, Zarkotou O, Sennati S, Politi L, Cannatelli A, et al. Characterization of extensively drug-resistant or pandrug-resistant sequence type 147 and 101 OXA-48-producing Klebsiella pneumoniae causing bloodstream infections in patients in an intensive care unit. Antimicrob Agents Chemother. 2018;62(7):e02457-17.  https://doi.org/10.1128/AAC.02457-17  PMID: 29661874 
  6. Brkic DV, Pristas I, Cipris I, Jelic M, Butic I, Andrasevic AT. Successful containment of the first KPC-producing Klebsiella pneumoniae outbreak in Croatia. Future Microbiol. 2017;12(11):967-74.  https://doi.org/10.2217/fmb-2016-0143  PMID: 28795847 
  7. Kaiser T, Finstermeier K, Häntzsch M, Faucheux S, Kaase M, Eckmanns T, et al. Stalking a lethal superbug by whole-genome sequencing and phylogenetics: Influence on unraveling a major hospital outbreak of carbapenem-resistant Klebsiella pneumoniae. Am J Infect Control. 2018;46(1):54-9.  https://doi.org/10.1016/j.ajic.2017.07.022  PMID: 28935481 
  8. Albiger B, Glasner C, Struelens MJ, Grundmann H, Monnet DLEuropean Survey of Carbapenemase-Producing Enterobacteriaceae (EuSCAPE) working group. Carbapenemase-producing Enterobacteriaceae in Europe: assessment by national experts from 38 countries, May 2015. Euro Surveill. 2015;20(45):30062.  https://doi.org/10.2807/1560-7917.ES.2015.20.45.30062  PMID: 26675038 
  9. Glasner C, Albiger B, Buist G, Tambić Andrasević A, Canton R, Carmeli Y, et al. Carbapenemase-producing Enterobacteriaceae in Europe: a survey among national experts from 39 countries, February 2013. Euro Surveill. 2013;18(28):20525.  https://doi.org/10.2807/1560-7917.ES2013.18.28.20525  PMID: 23870096 
  10. European Centre for Disease Prevention and Control (ECDC). Carbapenemase-producing bacteria in Europe. Interim results from the European survey on carbapenemase-producing Enterobacteriaceae (EuSCAPE) project 2013. Stockholm: ECDC; 2013. Available from: https://ecdc.europa.eu/sites/portal/files/media/en/publications/Publications/antimicrobial-resistance-carbapenemase-producing-bacteria-europe.pdf
  11. Grundmann H, Livermore DM, Giske CG, Canton R, Rossolini GM, Campos J, et al. Carbapenem-non-susceptible Enterobacteriaceae in Europe: conclusions from a meeting of national experts. Euro Surveill. 2010;15(46):19711.  https://doi.org/10.2807/ese.15.46.19711-en  PMID: 21144429 
  12. Pirš M, Cerar Kišek T, Križan Hergouth V, Seme K, Mueller Premru M, Jeverica S, et al. Successful control of the first OXA-48 and/or NDM carbapenemase-producing Klebsiella pneumoniae outbreak in Slovenia 2014-2016. J Hosp Infect. 2019;101(2):142-9.  https://doi.org/10.1016/j.jhin.2018.10.022  PMID: 30399389 
  13. Meletis G. Carbapenem resistance: overview of the problem and future perspectives. Ther Adv Infect Dis. 2016;3(1):15-21.  https://doi.org/10.1177/2049936115621709  PMID: 26862399 
  14. Grundmann H, Glasner C, Albiger B, Aanensen DM, Tomlinson CT, Andrasević AT, et al. Occurrence of carbapenemase-producing Klebsiella pneumoniae and Escherichia coli in the European survey of carbapenemase-producing Enterobacteriaceae (EuSCAPE): a prospective, multinational study. Lancet Infect Dis. 2017;17(2):153-63.  https://doi.org/10.1016/S1473-3099(16)30257-2  PMID: 27866944 
  15. European Centre for Disease Prevention and Control (ECDC). EU Laboratory Capability Monitoring System (EULabCap): Report on 2016 survey of EU/EEA country capabilities and capacities. Stockholm: ECDC; 2018. Available from: https://ecdc.europa.eu/en/publications-data/eu-laboratory-capability-monitoring-system-eulabcap-report-2016-survey-eueea
  16. European Centre for Disease Prevention and Control (ECDC). Monitoring the use of whole-genome sequencing in infectious disease surveillance in Europe 2015–2017. Stockholm: ECDC; 2018. Available from: https://www.ecdc.europa.eu/sites/portal/files/documents/whole-genome-sequencing-infectious-disease-surveillance-Europe-2015-2017.pdf
  17. European Centre for Disease Prevention and Control (ECDC). Carbapenemase-producing (OXA-48) Klebsiella pneumoniae ST392 in travellers previously hospitalised in Gran Canaria, Spain. Rapid risk assessment. Stockholm: ECDC; 2018. Available from: https://ecdc.europa.eu/sites/portal/files/documents/28-06-2018-RRA-Klebsiella-pneumoniae-Spain-Sweden-Finland-Norway.pdf
  18. Hrabák J, Papagiannitsis CC, Študentová V, Jakubu V, Fridrichová M, Zemlickova H, et al. Carbapenemase-producing Klebsiella pneumoniae in the Czech Republic in 2011. Euro Surveill. 2013;18(45):20626.  https://doi.org/10.2807/1560-7917.ES2013.18.45.20626  PMID: 24229789 
  19. Samuelsen Ø, Overballe-Petersen S, Bjørnholt JV, Brisse S, Doumith M, Woodford N, et al. Norwegian Study Group on CPE. Molecular and epidemiological characterization of carbapenemase-producing Enterobacteriaceae in Norway, 2007 to 2014. PLoS One. 2017;12(11):e0187832.  https://doi.org/10.1371/journal.pone.0187832  PMID: 29141051 
  20. European Centre for Disease Prevention and Control (ECDC). ECDC study protocol for genomic-based surveillance of carbapenem-resistant and/or colistin-resistant Enterobacteriaceae at the EU level. Version 2.0. Stockholm: ECDC; 2018. Available from: https://ecdc.europa.eu/en/publications-data/ecdc-study-protocol-genomic-based-surveillance-carbapenem-resistant-andor
Worsening epidemiological situation of carbapenemase-producing Enterobacteriaceae in Europe, assessment by national experts from 37 countries, July 2018
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Alma+Brolund&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Brolund Alma</a>, <a href="/search?value1=Nina+Lagerqvist&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Lagerqvist Nina</a>, <a href="/search?value1=Sara+Byfors&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Byfors Sara</a>, <a href="/search?value1=Marc+J+Struelens&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Struelens Marc J</a>, <a href="/search?value1=Dominique+L+Monnet&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Monnet Dominique L</a>, <a href="/search?value1=Barbara+Albiger&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Albiger Barbara</a>, <a href="/search?value1=Anke+Kohlenberg&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Kohlenberg Anke</a>, <a href="/search?value1=European+Antimicrobial+Resistance+Genes+Surveillance+Network+%28EURGen-Net%29+capacity+survey+group&option1=author&noRedirect=true" class="nonDisambigAuthorLink">European Antimicrobial Resistance Genes Surveillance Network (EURGen-Net) capacity survey group</a></span>. Worsening epidemiological situation of carbapenemase-producing Enterobacteriaceae in Europe, assessment by national experts from 37 countries, July 2018. <a href="/content/ecdc">Euro Surveill.</a> 2019;24(9):pii=1900123. <a href="https://doi.org/10.2807/1560-7917.ES.2019.24.9.1900123" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2019.24.9.1900123</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 15 Feb 2019;&nbsp;&nbsp; <span class="generated">Accepted</span>: 28 Feb 2019 </span> </p>
/content/10.2807/1560-7917.ES.2019.24.9.1900123
/content/10.2807/1560-7917.ES.2019.24.9.1900123
Loading

Data & Media loading...

Comment has been disabled for this content
Submit comment
Close
Comment moderation successfully completed
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error