- Chantal B.E.M. Reusken1,2, Eeva K. Broberg3, Bart Haagmans2, Adam Meijer1, Victor M. Corman4,5, Anna Papa6, Remi Charrel7, Christian Drosten4,5, Marion Koopmans2, Katrin Leitmeyer3, on behalf of EVD-LabNet and ERLI-Net8
-
View Affiliations Hide AffiliationsAffiliations: 1 Centre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, the Netherlands 2 Viroscience department, Erasmus MC, Rotterdam, the Netherlands 3 European Centre for Disease Prevention and Control, Solna, Sweden 4 Charité - Universitätsmedizin Berlin Institute of Virology, Berlin, Germany 5 German Centre for Infection Research (DZIF), Berlin, Germany 6 Department of Microbiology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece 7 Unité des Virus Emergents (Aix-Marseille Univ-IRD 190-Inserm 1207-IHU Méditerranée Infection), Marseille, France 8 The participating members of EVD-LabNet and ERLI-Net are acknowledged at the end of the articleCorrespondence:Chantal Reuskenchantal.reusken rivm.nl
-
View Citation Hide Citation
Citation style for this article: Reusken Chantal B.E.M., Broberg Eeva K., Haagmans Bart, Meijer Adam, Corman Victor M., Papa Anna, Charrel Remi, Drosten Christian, Koopmans Marion, Leitmeyer Katrin, on behalf of EVD-LabNet and ERLI-Net. Laboratory readiness and response for novel coronavirus (2019-nCoV) in expert laboratories in 30 EU/EEA countries, January 2020. Euro Surveill. 2020;25(6):pii=2000082. https://doi.org/10.2807/1560-7917.ES.2020.25.6.2000082 Received: 03 Feb 2020; Accepted: 11 Feb 2020
Laboratory readiness and response for novel coronavirus (2019-nCoV) in expert laboratories in 30 EU/EEA countries, January 2020
Abstract
Timely detection of novel coronavirus (2019-nCoV) infection cases is crucial to interrupt the spread of this virus. We assessed the required expertise and capacity for molecular detection of 2019-nCoV in specialised laboratories in 30 European Union/European Economic Area (EU/EEA) countries. Thirty-eight laboratories in 24 EU/EEA countries had diagnostic tests available by 29 January 2020. A coverage of all EU/EEA countries was expected by mid-February. Availability of primers/probes, positive controls and personnel were main implementation barriers.
Article metrics loading...
-
From This Site
/content/10.2807/1560-7917.ES.2020.25.6.2000082dcterms_title,dcterms_subject,pub_keyword105 -
PubMed
-
Google Scholar
Full text loading...
References
-
Tan WJ, Zhao X, Ma XJ, Wang W, Niu P, Xu W, et al. A novel coronavirus genome identified in a cluster of pneumonia cases — Wuhan, China 2019−2020. China CDC Weekly. 2020;2:61-2.
-
Novel 2019 coronavirus genome. [Accessed 02 Feb 2020]. Available from: http://virological.org/t/novel-2019-coronavirus-genome/319
-
European Centre for Disease Control and Prevention (ECDC). Novel coronavirus. Stockholm: ECDC. [Accessed 11 Feb 2020]. Available from: https://www.ecdc.europa.eu/en/novel-coronavirus-china
-
Rothe C, Schunk M, Sothmann P, Bretzel G, Froeschl G, Wallrauch C, et al. Transmission of 2019-nCoV Infection from an Asymptomatic Contact in Germany. N Engl J Med. 2020;NEJMc2001468. https://doi.org/10.1056/NEJMc2001468 PMID: 32003551
-
World Health Organization (WHO). Statement on the second meeting of the International Health Regulations (2005) Emergency Committee regarding the outbreak of novel coronavirus (2019-nCoV). Geneva: WHO; 30 Jan 2020. [Accessed 01 Feb 2020], Available from: https://www.who.int/news-room/detail/30-01-2020-statement-on-the-second-meeting-of-the-international-health-regulations-(2005)-emergency-committee-regarding-the-outbreak-of-novel-coronavirus-(2019-ncov)
-
Corman VM, Landt O, Kaiser M, Molenkamp R, Meijer A, Chu DK, et al. Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR. Euro Surveill. 2020;25(3):2000045. https://doi.org/10.2807/1560-7917.ES.2020.25.3.2000045 PMID: 31992387
-
World Health Organization (WHO). Novel Coronavirus. (2019-nCoV) technical guidance: laboratory guidance. Geneva: WHO. [Accessed 01 Feb 2020]. Available from: https://www.who.int/emergencies/diseases/novel-coronavirus-2019/technical-guidance/laboratory-guidance
-
Hadjinicolaou AV, Farcas GA, Demetriou VL, Mazzulli T, Poutanen SM, Willey BM, et al. Development of a molecular-beacon-based multi-allelic real-time RT-PCR assay for the detection of human coronavirus causing severe acute respiratory syndrome (SARS-CoV): a general methodology for detecting rapidly mutating viruses. Arch Virol. 2011;156(4):671-80. https://doi.org/10.1007/s00705-010-0906-7 PMID: 21221674
-
Romette JL, Prat CM, Gould EA, de Lamballerie X, Charrel R, Coutard B, et al. The European Virus Archive goes global: A growing resource for research. Antiviral Res. 2018;158:127-34. https://doi.org/10.1016/j.antiviral.2018.07.017 PMID: 30059721
-
European Centre for Disease Control and Prevention (ECDC). Novel coronavirus: case definition and European surveillance. Stockholm: ECDC. [Accessed 02 Feb 2020]. Available from: https://www.ecdc.europa.eu/en/case-definition-and-european-surveillance-human-infection-novel-coronavirus-2019-ncov
-
Pullano G, Pinotti F, Valdano E, Boëlle P-Y, Poletto C, Colizza V. Novel coronavirus (2019-nCoV) early-stage importation risk to Europe, January 2020. Euro Surveill. 2020;25(4):2000057. https://doi.org/10.2807/1560-7917.ES.2020.25.4.2000057 PMID: 32019667
-
Chinazzi M, Davis JT, Gioannini C, Litvinova M, Pastore y Piontti A, Rossi L, et al. Preliminary assessment of the International Spreading Risk Associated with the 2019 novel Coronavirus (2019-nCoV) outbreak in Wuhan City. Available from: https://www.mobs-lab.org/uploads/6/7/8/7/6787877/wuhan_novel_coronavirus__6_.pdf
-
Lai S, Bogoch II, Watts A, Khan K, Li Z, Tatem A. Preliminary risk analysis of 2019 novel coronavirus spread within and beyond China. Available from: https://www.worldpop.org/resources/docs/china/WorldPop-coronavirus-spread-risk-analysis-v1-25Jan.pdf
-
Bogoch II, Watts A, Thomas-Bachli A, Huber C, Kraemer MUG, Khan K. Pneumonia of Unknown Etiology in Wuhan, China: Potential for International Spread Via Commercial Air Travel. J Travel Med. 2020;taaa008. https://doi.org/10.1093/jtm/taaa008 PMID: 31943059
-
Mögling R, Zeller H, Revez J, Koopmans M, Reusken CZIKV reference laboratory group. Status, quality and specific needs of Zika virus (ZIKV) diagnostic capacity and capability in National Reference Laboratories for arboviruses in 30 EU/EEA countries, May 2016. Euro Surveill. 2017;22(36):30609. https://doi.org/10.2807/1560-7917.ES.2017.22.36.30609 PMID: 28920574
-
World Health Organization (WHO). Novel Coronavirus. (2019-nCoV) technical guidance: Early investigations. Geneva: WHO. [Accessed 01 Feb 2020]. Available from: https://www.who.int/emergencies/diseases/novel-coronavirus-2019/technical-guidance/early-investigations
-
Charrel R, Mögling R, Pas S, Papa A, Baronti C, Koopmans M, et al. Variable Sensitivity in Molecular Detection of Zika Virus in European Expert Laboratories: External Quality Assessment, November 2016. J Clin Microbiol. 2017;55(11):3219-26. https://doi.org/10.1128/JCM.00987-17 PMID: 28835479
-
Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020;S0140-6736(20)30183-5. https://doi.org/10.1016/S0140-6736(20)30183-5 PMID: 31986264
Data & Media loading...

