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Abstract

Timely detection of novel coronavirus (2019-nCoV) infection cases is crucial to interrupt the spread of this virus. We assessed the required expertise and capacity for molecular detection of 2019-nCoV in specialised laboratories in 30 European Union/European Economic Area (EU/EEA) countries. Thirty-eight laboratories in 24 EU/EEA countries had diagnostic tests available by 29 January 2020. A coverage of all EU/EEA countries was expected by mid-February. Availability of primers/probes, positive controls and personnel were main implementation barriers.

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/content/10.2807/1560-7917.ES.2020.25.6.2000082
2020-02-13
2020-04-02
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2020.25.6.2000082
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References

  1. Tan WJ, Zhao X, Ma XJ, Wang W, Niu P, Xu W, et al. A novel coronavirus genome identified in a cluster of pneumonia cases — Wuhan, China 2019−2020. China CDC Weekly. 2020;2:61-2.
  2. Novel 2019 coronavirus genome. [Accessed 02 Feb 2020]. Available from: http://virological.org/t/novel-2019-coronavirus-genome/319
  3. European Centre for Disease Control and Prevention (ECDC). Novel coronavirus. Stockholm: ECDC. [Accessed 11 Feb 2020]. Available from: https://www.ecdc.europa.eu/en/novel-coronavirus-china
  4. Rothe C, Schunk M, Sothmann P, Bretzel G, Froeschl G, Wallrauch C, et al. Transmission of 2019-nCoV Infection from an Asymptomatic Contact in Germany. N Engl J Med. 2020;NEJMc2001468.  https://doi.org/10.1056/NEJMc2001468  PMID: 32003551 
  5. World Health Organization (WHO). Statement on the second meeting of the International Health Regulations (2005) Emergency Committee regarding the outbreak of novel coronavirus (2019-nCoV). Geneva: WHO; 30 Jan 2020. [Accessed 01 Feb 2020], Available from: https://www.who.int/news-room/detail/30-01-2020-statement-on-the-second-meeting-of-the-international-health-regulations-(2005)-emergency-committee-regarding-the-outbreak-of-novel-coronavirus-(2019-ncov)
  6. Corman VM, Landt O, Kaiser M, Molenkamp R, Meijer A, Chu DK, et al. Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR. Euro Surveill. 2020;25(3):2000045.  https://doi.org/10.2807/1560-7917.ES.2020.25.3.2000045  PMID: 31992387 
  7. World Health Organization (WHO). Novel Coronavirus. (2019-nCoV) technical guidance: laboratory guidance. Geneva: WHO. [Accessed 01 Feb 2020]. Available from: https://www.who.int/emergencies/diseases/novel-coronavirus-2019/technical-guidance/laboratory-guidance
  8. Hadjinicolaou AV, Farcas GA, Demetriou VL, Mazzulli T, Poutanen SM, Willey BM, et al. Development of a molecular-beacon-based multi-allelic real-time RT-PCR assay for the detection of human coronavirus causing severe acute respiratory syndrome (SARS-CoV): a general methodology for detecting rapidly mutating viruses. Arch Virol. 2011;156(4):671-80.  https://doi.org/10.1007/s00705-010-0906-7  PMID: 21221674 
  9. Romette JL, Prat CM, Gould EA, de Lamballerie X, Charrel R, Coutard B, et al. The European Virus Archive goes global: A growing resource for research. Antiviral Res. 2018;158:127-34.  https://doi.org/10.1016/j.antiviral.2018.07.017  PMID: 30059721 
  10. European Centre for Disease Control and Prevention (ECDC). Novel coronavirus: case definition and European surveillance. Stockholm: ECDC. [Accessed 02 Feb 2020]. Available from: https://www.ecdc.europa.eu/en/case-definition-and-european-surveillance-human-infection-novel-coronavirus-2019-ncov
  11. Pullano G, Pinotti F, Valdano E, Boëlle P-Y, Poletto C, Colizza V. Novel coronavirus (2019-nCoV) early-stage importation risk to Europe, January 2020. Euro Surveill. 2020;25(4):2000057.  https://doi.org/10.2807/1560-7917.ES.2020.25.4.2000057  PMID: 32019667 
  12. Chinazzi M, Davis JT, Gioannini C, Litvinova M, Pastore y Piontti A, Rossi L, et al. Preliminary assessment of the International Spreading Risk Associated with the 2019 novel Coronavirus (2019-nCoV) outbreak in Wuhan City. Available from: https://www.mobs-lab.org/uploads/6/7/8/7/6787877/wuhan_novel_coronavirus__6_.pdf
  13. Lai S, Bogoch II, Watts A, Khan K, Li Z, Tatem A. Preliminary risk analysis of 2019 novel coronavirus spread within and beyond China. Available from: https://www.worldpop.org/resources/docs/china/WorldPop-coronavirus-spread-risk-analysis-v1-25Jan.pdf
  14. Bogoch II, Watts A, Thomas-Bachli A, Huber C, Kraemer MUG, Khan K. Pneumonia of Unknown Etiology in Wuhan, China: Potential for International Spread Via Commercial Air Travel. J Travel Med. 2020;taaa008.  https://doi.org/10.1093/jtm/taaa008  PMID: 31943059 
  15. Mögling R, Zeller H, Revez J, Koopmans M, Reusken CZIKV reference laboratory group. Status, quality and specific needs of Zika virus (ZIKV) diagnostic capacity and capability in National Reference Laboratories for arboviruses in 30 EU/EEA countries, May 2016. Euro Surveill. 2017;22(36):30609.  https://doi.org/10.2807/1560-7917.ES.2017.22.36.30609  PMID: 28920574 
  16. World Health Organization (WHO). Novel Coronavirus. (2019-nCoV) technical guidance: Early investigations. Geneva: WHO. [Accessed 01 Feb 2020]. Available from: https://www.who.int/emergencies/diseases/novel-coronavirus-2019/technical-guidance/early-investigations
  17. Charrel R, Mögling R, Pas S, Papa A, Baronti C, Koopmans M, et al. Variable Sensitivity in Molecular Detection of Zika Virus in European Expert Laboratories: External Quality Assessment, November 2016. J Clin Microbiol. 2017;55(11):3219-26.  https://doi.org/10.1128/JCM.00987-17  PMID: 28835479 
  18. Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020;S0140-6736(20)30183-5. https://doi.org/10.1016/S0140-6736(20)30183-5  PMID: 31986264 
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