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Abstract

An outbreak caused by the SARS-CoV-2 Delta variant (B.1.617.2) spread from one inpatient in a secondary care hospital to three primary care facilities, resulting in 58 infections including 18 deaths in patients and 45 infections in healthcare workers (HCW). Only one of the deceased cases was fully vaccinated. Transmission occurred despite the use of personal protective equipment by the HCW, as advised in national guidelines, and a high two-dose COVID-19 vaccination coverage among permanent staff members in the COVID-19 cohort ward.

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/content/10.2807/1560-7917.ES.2021.26.30.2100636
2021-07-29
2024-12-13
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2021.26.30.2100636
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References

  1. European Centre for Disease Prevention and Control (ECDC). Threat Assessment Brief: Implications for the EU/EEA on the spread of the SARS-CoV-2 Delta (B.1.617.2) variant of concern. Stockholm: ECDC; 2021. Available from: https://www.ecdc.europa.eu/en/publications-data/threat-assessment-emergence-and-impact-sars-cov-2-delta-variant
  2. Davies NG, Abbott S, Barnard RC, Jarvis CI, Kucharski AJ, Munday JD, et al. Estimated transmissibility and impact of SARS-CoV-2 lineage B.1.1.7 in England. Science. 2021;372(6538):eabg3055.  https://doi.org/10.1126/science.abg3055  PMID: 33658326 
  3. Ferguson NMB. 1.617.2 transmission in England: risk factors and transmission advantage. London: Imperial College London; 2021. Available from: https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/993159/S1270_IMPERIAL_B.1.617.2.pdf
  4. Leung K, Shum MH, Leung GM, Lam TT, Wu JT. Early transmissibility assessment of the N501Y mutant strains of SARS-CoV-2 in the United Kingdom, October to November 2020. Euro Surveill. 2021;26(1):2002106.  https://doi.org/10.2807/1560-7917.ES.2020.26.1.2002106  PMID: 33413740 
  5. Shu Y, McCauley J. GISAID: Global initiative on sharing all influenza data - from vision to reality. Euro Surveill. 2017;22(13):30494.  https://doi.org/10.2807/1560-7917.ES.2017.22.13.30494  PMID: 28382917 
  6. Binnicker MJ. Challenges and Controversies to Testing for COVID-19. J Clin Microbiol. 2020;58(11):e01695-20.  https://doi.org/10.1128/JCM.01695-20  PMID: 32817231 
  7. Meyerowitz EA, Richterman A, Gandhi RT, Sax PE. Transmission of SARS-CoV-2: a review of viral, host, and environmental factors. Ann Intern Med. 2021;174(1):69-79.  https://doi.org/10.7326/M20-5008  PMID: 32941052 
  8. Adam DC, Wu P, Wong JY, Lau EHY, Tsang TK, Cauchemez S, et al. Clustering and superspreading potential of SARS-CoV-2 infections in Hong Kong. Nat Med. 2020;26(11):1714-9.  https://doi.org/10.1038/s41591-020-1092-0  PMID: 32943787 
  9. Fang FC, Benson CA, Del Rio C, Edwards KM, Fowler VG Jr, Fredricks DN, et al. COVID-19—lessons learned and questions remaining. Clin Infect Dis. 2021;72(12):2225-40.  https://doi.org/10.1093/cid/ciaa1654  PMID: 33104186 
  10. Marks M, Millat-Martinez P, Ouchi D, Roberts CH, Alemany A, Corbacho-Monné M, et al. Transmission of COVID-19 in 282 clusters in Catalonia, Spain: a cohort study. Lancet Infect Dis. 2021;21(5):629-36.  https://doi.org/10.1016/S1473-3099(20)30985-3  PMID: 33545090 
  11. Lopez Bernal J, Andrews N, Gower C, Gallagher E, Simmons R, Thelwall S, et al. Effectiveness of Covid-19 Vaccines against the B.1.617.2 (Delta) variant. N Engl J Med. 2021;NEJMoa2108891.  https://doi.org/10.1056/NEJMoa2108891  PMID: 34289274 
  12. Stowe J, Andrews N, Gower C, Gallagher E, Utsi L, Simmons R, et al. Effectiveness of COVID-19 vaccines against hospital admission with the Delta (B.1.617.2) variant. London: Public Health England; 2021. Pre-print. Available from: https://khub.net/web/phe-national/public-library/-/document_library/v2WsRK3ZlEig/view/479607266
  13. Chu DK, Akl EA, Duda S, Solo K, Yaacoub S, Schünemann HJ, et al. Physical distancing, face masks, and eye protection to prevent person-to-person transmission of SARS-CoV-2 and COVID-19: a systematic review and meta-analysis. Lancet. 2020;395(10242):1973-87.  https://doi.org/10.1016/S0140-6736(20)31142-9  PMID: 32497510 
  14. Oksanen LAH, Sanmark E, Oksanen SA, Anttila VJ, Paterno JJ, Lappalainen M, et al. Sources of healthcare workers’ COVID‑19 infections and related safety guidelines. Int J Occup Med Environ Health. 2021;34(2):239-49.  https://doi.org/10.13075/ijomeh.1896.01741  PMID: 33847307 
  15. Hamilton F, Arnold D, Bzdek BR, Dodd J, Reid J, Maskell N, et al. Aerosol generating procedures: are they of relevance for transmission of SARS-CoV-2? Lancet Respir Med. 2021;9(7):687-9.  https://doi.org/10.1016/S2213-2600(21)00216-2  PMID: 33965002 
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