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Abstract

Introduction

Knowing the factors associated with HIV transmission is necessary in order to design preventive programmes tailored to the epidemiological situation in each region and population.

Aim

Our objective was to study the sociodemographic, clinical and behavioural characteristics of men who have sex with men (MSM) who were newly diagnosed with HIV infection.

Methods

We carried out an observational, descriptive, study on all MSM newly diagnosed with HIV infection in one clinic for sexually transmitted infections (STI) and HIV clinic in Madrid between 2014 and 2019. Information on sociodemographic, clinical, and behavioural characteristics of participants per year of diagnosis was collected.

Results

We detected a total of 1,398 people with HIV infection, 253 of whom were recent seroconverters (rSCV) with a median duration of documented seroconversion of 6 months. From the total, 97.9% infections were sexually transmitted and 2.1% involved injected drugs, i.e. slam practices. The average age was 32.9 years (range: 15.6–74.9), 51.8% were Spanish and 40% Latin American. These diagnoses decreased in Spanish people and increased in Latin Americans during the study period. Of the rSCV, 73.9% had condomless sex under the influence of drugs and 28.9% participated in chemsex sessions. Apps were used by 92.6% rSCV for sexual encounters and 70.4% of them attributed HIV transmission to their use.

Conclusions

Combination of HIV prevention strategies, as pre-exposure prophylaxis, should be reinforced among young MSM, especially those born in Latin America, those who use drugs for sex, and those who use apps in search of sexual contacts.

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/content/10.2807/1560-7917.ES.2021.26.47.2001501
2021-11-25
2021-11-28
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2021.26.47.2001501
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References

  1. Centers for Disease Control (CDC). Pneumocystis pneumonia--Los Angeles. MMWR Morb Mortal Wkly Rep. 1981;30(21):250-2. PMID: 6265753 
  2. Marks G, Crepaz N, Janssen RS. Estimating sexual transmission of HIV from persons aware and unaware that they are infected with the virus in the USA. AIDS. 2006;20(10):1447-50.  https://doi.org/10.1097/01.aids.0000233579.79714.8d  PMID: 16791020 
  3. Kolata G. FDA approves AZT. Science. 1987;235(4796):1570.  https://doi.org/10.1126/science.235.4796.1570-b  PMID: 3469754 
  4. Carpenter CC, Fischl MA, Hammer SM, Hirsch MS, Jacobsen DM, Katzenstein DA, et al. Antiretroviral therapy for HIV infection in 1996. Recommendations of an international panel. International AIDS Society-USA. JAMA. 1996;276(2):146-54.  https://doi.org/10.1001/jama.1996.03540020068031  PMID: 8656507 
  5. INSIGHT START Study GroupLundgren JD, Babiker AG, Gordin F, Emery S, Grund B, et al. . Initiation of Antiretroviral Therapy in Early Asymptomatic HIV Infection. N Engl J Med. 2015;373(9):795-807.  https://doi.org/10.1056/NEJMoa1506816  PMID: 26192873 
  6. Cohen MS, Chen YQ, McCauley M, Gamble T, Hosseinipour MC, Kumarasamy N, et al. Prevention of HIV-1 infection with early antiretroviral therapy. N Engl J Med. 2011;365(6):493-505.  https://doi.org/10.1056/NEJMoa1105243  PMID: 21767103 
  7. Rodger AJ, Cambiano V, Bruun T, Vernazza P, Collins S, Degen O, et al. Risk of HIV transmission through condomless sex in serodifferent gay couples with the HIV-positive partner taking suppressive antiretroviral therapy (PARTNER): final results of a multicentre, prospective, observational study. Lancet. 2019;393(10189):2428-38.  https://doi.org/10.1016/S0140-6736(19)30418-0  PMID: 31056293 
  8. Grant RM, Lama JR, Anderson PL, McMahan V, Liu AY, Vargas L, et al. Preexposure chemoprophylaxis for HIV prevention in men who have sex with men. N Engl J Med. 2010;363(27):2587-99.  https://doi.org/10.1056/NEJMoa1011205  PMID: 21091279 
  9. European Medicines Agency (EMA). First medicine for HIV pre-exposure prophylaxis recommended for approval in the EU. EMA/CHMP/496941/2016. London: EMA; 2016. Available from: https://www.ema.europa.eu/en/news/first-medicine-hiv-pre-exposure-prophylaxis-recommended-approval-eu
  10. Center for Disease Control and Prevention (CDC). Preexposure prophylaxis for the prevention of HIV Infection in the United State – 2017 update. A clinical practice guideline. Atlanta: CDC; 2017. Available from: https://www.cdc.gov/hiv/pdf/risk/prep/cdc-hiv-prep-guidelines-2017.pdf
  11. World Health Organization (WHO). Policy brief: pre-exposure prophylaxis (‎PrEP)‎: WHO expands recommendation on oral pre- exposure prophylaxis of HIV infection (PrEP). Geneva: WHO; 2015. Available from: https://apps.who.int/iris/handle/10665/197906
  12. European AIDS Clinical Society (EACS). Guidelines. Version 9.0. Brussels: EACS; 2017. Available from: http://www.eacsociety.org/files/guidelines_9.0-english.pdf
  13. Grupo de Estudio de Sida de la SEIMC (GeSIDA). Recomendaciones sobre Profilaxis Pre-Exposición en adultos para la Prevención de la Infección por VIH en España. [Recommendations on pre-exposure prophylaxis in adults for the prevention of HIV infection in Spain]. Madrid: GeSIDA; 2017. Spanish. Available from: https://gesida-seimc.org/wp-content/uploads/2017/02/gesida-guiasclinicas-2016-profilaxis_pre-exposicionVIH.pdf
  14. de Sanidad M, Consumo y Bienestar S. Notas de Prensa. El Sistema Nacional de Salud (SNS) financia la PrEP desde mañana como medida de prevención del VIH en personas de alto riesgo. [Press release. The National Health System (SNS) finances PrEP starting tomorrow as an HIV prevention measure in people at high risk]. Madrid: Ministerio de Sanidad; 2019. Spanish. Available from: https://www.mscbs.gob.es/gabinete/notasPrensa.do?id=4708
  15. UNAIDS. Global HIV & AIDS statistics — 2020 fact sheet. Geneva: UNAIDS. [Accessed: Dec 2020]. Available from: http://unaids.mio.guru/en/resources/fact-sheet
  16. Grulich AE, Guy R, Amin J, Jin F, Selvey C, Holden J, et al. Population-level effectiveness of rapid, targeted, high-coverage roll-out of HIV pre-exposure prophylaxis in men who have sex with men: the EPIC-NSW prospective cohort study. Lancet HIV. 2018;5(11):e629-37.  https://doi.org/10.1016/S2352-3018(18)30215-7  PMID: 30343026 
  17. Epidemiology Section HIV. HIV epidemiology annual report 2019. San Francisco: San Francisco Department of Public Health; 2020. Available from: https://www.sfdph.org/dph/files/reports/RptsHIVAIDS/AnnualReport2019_Indigo_20200929_Web_fixed.pdf
  18. Brown AE, Mohammed H, Ogaz D, Kirwan PD, Yung M, Nash SG, et al. Fall in new HIV diagnoses among men who have sex with men (MSM) at selected London sexual health clinics since early 2015: testing or treatment or pre-exposure prophylaxis (PrEP)? Euro Surveill. 2017;22(25):30553.  https://doi.org/10.2807/1560-7917.ES.2017.22.25.30553  PMID: 28662762 
  19. European Centre for Disease Prevention and Control (ECDC), World Health Organization Regional Office for Europe. (WHO/Europe). HIV/AIDS surveillance in Europe 2019 - 2018 data. Stockholm: ECDC; Copenhagen: WHO/Europe; 2019. Available from: https://www.ecdc.europa.eu/en/publications-data/hivaids-surveillance-europe-2019-2018-data
  20. Unidad de Vigilancia de VIH. ITS y hepatitis. Vigilancia Epidemiológica del VIH y sida en España 2019: Sistema de Información sobre Nuevos Diagnósticos de VIH y Registro Nacional de Casos de Sida. Plan Nacional sobre el Sida. [Epidemiological surveillance of HIV and AIDS in Spain 2019: information system on new HIV diagnoses and national registry of AIDS cases. National Plan on AIDS]. Madrid:D.G. de Salud Pública / Centro Nacional de Epidemiología - ISCIII; 2020. Spanish. Available from: https://www.mscbs.gob.es/ciudadanos/enfLesiones/enfTransmisibles/sida/vigilancia/home.htm
  21. Public Health England (PHE). Trends in HIV testing, new diagnoses and people receiving HIV-related care in the UK: data to the end of December 2019. Health Protection Report. 2020;14(20). Available from: http://allcatsrgrey.org.uk/wp/wpfb-file/hpr2020_hiv19-pdf/
  22. World Health Organization (WHO). Global health sector strategy on HIV 2016-2021. Towards ending AIDS. Geneva: WHO; 2016. Available from: https://www.who.int/publications/i/item/WHO-HIV-2016.05
  23. Hegazi A, Lee MJ, Whittaker W, Green S, Simms R, Cutts R, et al. Chemsex and the city: sexualised substance use in gay bisexual and other men who have sex with men attending sexual health clinics. Int J STD AIDS. 2017;28(4):362-6.  https://doi.org/10.1177/0956462416651229  PMID: 27178067 
  24. Maxwell S, Shahmanesh M, Gafos M. Chemsex behaviours among men who have sex with men: A systematic review of the literature. Int J Drug Policy. 2019;63:74-89.  https://doi.org/10.1016/j.drugpo.2018.11.014  PMID: 30513473 
  25. González-Baeza A, Dolengevich-Segal H, Pérez-Valero I, Cabello A, Téllez MJ, Sanz J, et al. Sexualized Drug Use (Chemsex) Is Associated with High-Risk Sexual Behaviors and Sexually Transmitted Infections in HIV-Positive Men Who Have Sex with Men: Data from the U-SEX GESIDA 9416 Study. AIDS Patient Care STDS. 2018;32(3):112-8.  https://doi.org/10.1089/apc.2017.0263  PMID: 29620925 
  26. Pakianathan M, Whittaker W, Lee MJ, Avery J, Green S, Nathan B, et al. Chemsex and new HIV diagnosis in gay, bisexual and other men who have sex with men attending sexual health clinics. HIV Med. 2018;19(7):485-90.  https://doi.org/10.1111/hiv.12629  PMID: 29790254 
  27. Bui H, Zablotska-Manos I, Hammoud M, Jin F, Lea T, Bourne A, et al. Prevalence and correlates of recent injecting drug use among gay and bisexual men in Australia: Results from the FLUX study. Int J Drug Policy. 2018;55:222-30.  https://doi.org/10.1016/j.drugpo.2018.01.018  PMID: 29429864 
  28. Ayerdi Aguirrebengoa O, Vera García M, Portocarrero Nuñez JA, Puerta López T, García Lotero M, Escalante Garcia C, et al. Implementing pre-exposure prophylaxis could prevent most new HIV infections in transsexual women and men who have sex with men. Rev Clin Esp (Barc). 2019;219(7):360-6.  https://doi.org/10.1016/j.rceng.2019.02.010  PMID: 30982539 
  29. Francisco Luz Nunes Queiroz AA, Lopes de Sousa ÁF, Evangelista de Araújo TM, Milanez de Oliveira FB, Batista Moura ME, Reis RK. A Review of Risk Behaviors for HIV Infection by Men Who Have Sex With Men Through Geosocial Networking Phone Apps. J Assoc Nurses AIDS Care. 2017;28(5):807-18.  https://doi.org/10.1016/j.jana.2017.03.009  PMID: 28456472 
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