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Abstract

Serum samples were collected pre- and post-booster vaccination with Comirnaty in 626 participants (aged ≥ 50 years) who had received two Comirnaty doses < 30 days apart, two Comirnaty doses ≥ 30 days apart or two Vaxzevria doses ≥ 30 days apart. Irrespective of primary vaccine type or schedule, spike antibody GMTs peaked 2–4 weeks after second dose, fell significantly ≤ 38 weeks later and rose above primary immunisation GMTs 2–4 weeks post-booster. Higher post-booster responses were observed with a longer interval between primary immunisation and boosting.

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/content/10.2807/1560-7917.ES.2022.27.1.2101114
2022-01-06
2024-04-25
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2022.27.1.2101114
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Serological responses to COVID-19 Comirnaty booster vaccine, London, United Kingdom, September to December 2021
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Georgina+Ireland&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Ireland Georgina</a>, <a href="/search?value1=Heather+Whitaker&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Whitaker Heather</a>, <a href="/search?value1=Shamez+N+Ladhani&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Ladhani Shamez N</a>, <a href="/search?value1=Frances+Baawuah&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Baawuah Frances</a>, <a href="/search?value1=Sathyvani+Subbarao&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Subbarao Sathyvani</a>, <a href="/search?value1=Ezra+Linley&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Linley Ezra</a>, <a href="/search?value1=Lenesha+Warrener&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Warrener Lenesha</a>, <a href="/search?value1=Michelle+O%E2%80%99Brien&option1=author&noRedirect=true" class="nonDisambigAuthorLink">O’Brien Michelle</a>, <a href="/search?value1=Corinne+Whillock&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Whillock Corinne</a>, <a href="/search?value1=Oliver+Martin&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Martin Oliver</a>, <a href="/search?value1=Paul+Moss&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Moss Paul</a>, <a href="/search?value1=Mary+E+Ramsay&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Ramsay Mary E</a>, <a href="/search?value1=Gayatri+Amirthalingam&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Amirthalingam Gayatri</a>, <a href="/search?value1=Kevin+E+Brown&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Brown Kevin E</a></span>. Serological responses to COVID-19 Comirnaty booster vaccine, London, United Kingdom, September to December 2021. <a href="/content/ecdc">Euro Surveill.</a> 2022;27(1):pii=2101114. <a href="https://doi.org/10.2807/1560-7917.ES.2022.27.1.2101114" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2022.27.1.2101114</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 06 Dec 2021;&nbsp;&nbsp; <span class="generated">Accepted</span>: 21 Dec 2021 </span> </p>
/content/10.2807/1560-7917.ES.2022.27.1.2101114
/content/10.2807/1560-7917.ES.2022.27.1.2101114
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