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Monkeypox 2022
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10 results
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Evidence of surface contamination in hospital rooms occupied by patients infected with monkeypox, Germany, June 2022
The extent of monkeypox virus environmental contamination of surfaces is unclear. We examined surfaces in rooms occupied by two monkeypox patients on their fourth hospitalisation day. Contamination with up to 105 viral copies/cm2 on inanimate surfaces was estimated by PCR and the virus was successfully isolated from surfaces with more than 106 copies. These data highlight the importance of strict adherence of hospital staff to recommended protective measures. If appropriate, pre-exposure or early post-exposure vaccination should be considered for individuals at risk.
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Estimated incubation period for monkeypox cases confirmed in the Netherlands, May 2022
In May 2022, monkeypox outbreaks have been reported in countries not endemic for monkeypox. We estimated the monkeypox incubation period, using reported exposure and symptom-onset times for 18 cases detected and confirmed in the Netherlands up to 31 May 2022. Mean incubation period was 8.5 days (5th–95th percentiles: 4.2–17.3), underpinning the current recommendation to monitor or isolate/quarantine case contacts for 21 days. However, as the incubation period may differ between different transmission routes, further epidemiological investigations are needed.
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Community transmission of monkeypox in the United Kingdom, April to May 2022
Roberto Vivancos , Charlotte Anderson , Paula Blomquist , Sooria Balasegaram , Anita Bell , Louise Bishop , Colin S Brown , Yimmy Chow , Obaghe Edeghere , Isaac Florence , Sarah Logan , Petra Manley , William Crowe , Andrew McAuley , Ananda Giri Shankar , Borja Mora-Peris , Karthik Paranthaman , Mateo Prochazka , Cian Ryan , David Simons , Richard Vipond , Chloe Byers , Nicholas A. Watkins , UKHSA Monkeypox Incident Management team , Will Welfare , Elizabeth Whittaker , Claire Dewsnap , Allegra Wilson , Yvonne Young , Meera Chand , Steven Riley and Susan HopkinsBetween 7 and 25 May, 86 monkeypox cases were confirmed in the United Kingdom (UK). Only one case is known to have travelled to a monkeypox virus (MPXV) endemic country. Seventy-nine cases with information were male and 66 reported being gay, bisexual, or other men who have sex with men. This is the first reported sustained MPXV transmission in the UK, with human-to-human transmission through close contacts, including in sexual networks. Improving case ascertainment and onward-transmission preventive measures are ongoing.
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Epidemiological, clinical and virological characteristics of four cases of monkeypox support transmission through sexual contact, Italy, May 2022
Andrea Antinori , Valentina Mazzotta , Serena Vita , Fabrizio Carletti , Danilo Tacconi , Laura Emma Lapini , Alessandra D’Abramo , Stefania Cicalini , Daniele Lapa , Silvia Pittalis , Vincenzo Puro , Marco Rivano Capparuccia , Emanuela Giombini , Cesare Ernesto Maria Gruber , Anna Rosa Garbuglia , Alessandra Marani , Francesco Vairo , Enrico Girardi , Francesco Vaia , Emanuele Nicastri and the INMI Monkeypox GroupSince May 2022, an outbreak of monkeypox has been ongoing in non-endemic countries. We report four cases in Italy in young adult men reporting condomless sexual intercourse. The patients are in good clinical condition with no need for specific antiviral drugs. Biological samples from seminal fluid were positive for monkeypox viral DNA. For many other viruses found in semen there is no evidence of sexual transmission. The possibility of sexual transmission of monkeypox virus needs to be investigated.
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Monkeypox infection presenting as genital rash, Australia, May 2022
Rapid diagnosis and whole genome sequencing confirmed a case of monkeypox in an HIV-positive individual receiving antiretroviral therapy. The patient had a normal CD4+ T-cell count and suppressed HIV viral load and presented with a genital rash in Melbourne, Australia after return from Europe in May 2022. He subsequently developed systemic illness and disseminated rash and 11 days after symptom onset, he was hospitalised to manage painful bacterial cellulitis of the genital area.
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Ongoing monkeypox virus outbreak, Portugal, 29 April to 23 May 2022
Mariana Perez Duque , Sofia Ribeiro , João Vieira Martins , Pedro Casaca , Pedro Pinto Leite , Margarida Tavares , Kamal Mansinho , Luís Miguel Duque , Cândida Fernandes , Rita Cordeiro , Maria José Borrego , Ana Pelerito , Isabel Lopes de Carvalho , Sofia Núncio , Vera Manageiro , Corrado Minetti , Jorge Machado , Joana M Haussig , Roberto Croci , Gianfranco Spiteri , Ana Sofia Casal , Diana Mendes , Tiago Souto , Sara Pocinho , Teresa Fernandes , Ana Firme , Paula Vasconcelos and Graça FreitasUp to 27 May 2022, Portugal has detected 96 confirmed cases of monkeypox. We describe 27 confirmed cases (median age: 33 years (range: 22–51); all males), with an earliest symptom onset date of 29 April. Almost all cases (n = 25) live in the Lisbon and Tagus Valley health region. Most cases were neither part of identified transmission chains, nor linked to travel or had contact with symptomatic persons or with animals, suggesting the possible previously undetected spread of monkeypox.
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Family cluster of three cases of monkeypox imported from Nigeria to the United Kingdom, May 2021
Most reported cases of human monkeypox occur in Central and West Africa, where the causing virus is endemic. We describe the identification and public health response to an imported case of West African monkeypox from Nigeria to the United Kingdom (UK) in May 2021. Secondary transmission from the index case occurred within the family to another adult and a toddler. Concurrent COVID-19-related control measures upon arrival and at the hospital, facilitated detection and limited the number of potential contacts.
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Two cases of monkeypox imported to the United Kingdom, September 2018
Aisling Vaughan , Emma Aarons , John Astbury , Sooria Balasegaram , Mike Beadsworth , Charles R Beck , Meera Chand , Catherine O’Connor , Jake Dunning , Sam Ghebrehewet , Nick Harper , Ruth Howlett-Shipley , Chikwe Ihekweazu , Michael Jacobs , Lukeki Kaindama , Parisha Katwa , Saye Khoo , Lucy Lamb , Sharon Mawdsley , Dilys Morgan , Ruth Palmer , Nick Phin , Katherine Russell , Bengü Said , Andrew Simpson , Roberto Vivancos , Michael Wade , Amanda Walsh and Jennifer WilburnIn early September 2018, two cases of monkeypox were reported in the United Kingdom (UK), diagnosed on 7 September in Cornwall (South West England) and 11 September in Blackpool (North West England). The cases were epidemiologically unconnected and had recently travelled to the UK from Nigeria, where monkeypox is currently circulating. We describe the epidemiology and the public health response for the first diagnosed cases outside the African continent since 2003.
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